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In the froth floatation method, the role of depressants is to prevent certain types of particles from forming the froth with the air bubbles. For example, NaCN is used as a depressant to separate lead sulfide ore (PbS) from zinc Sulphide ore (ZnS).NaCN forms a zinc complex Na2[Zn(CN)4] on the surface of ZnS thereby preventing it from the formation of froth.
4 NaCN + ZnS -----Na2[Zn(CN)4]
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