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Discuss the transport of gases (O2 and CO2) in the blood ?
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Transport of respiratory gases in the blood:
Blood is the medium of transport for O2 and CO2.
(i) Tranport of oxygen
- About 97% of the oxygen is transported by the erythrocytes in the form of
oxyhaemoglobin and 3% is carried in a dissolved form in the plasma.
- Oxygen binds with the Fe2+ part of the haemoglobin in a reversible manner to
form oxyhaemoglobin.
- Each haemoglobin molecule can carry a maximum of four molecules of oxygen.
(ii) Transport of carbon dioxide
- About 4 ml of carbon dioxide is transported by 100 ml of blood.
It is transported in three forms:
(i) In the dissolved form in the plasma (5-7%).
(ii) As bicarbonates in the plasma and in the erythrocytes (70%).
(iii) As carbaminohaemoglobin in the erythrocytes (23%).
- In the erythrocytes, carbonic anhydrase catalyses the formation of bicarbonates
from carbon dioxide and water.
- Most of the bicarbonates leak out into plasma in exchange of Cl- ions.
- In the plasma CO2 is carried in the form of sodium bicarbonate while in the
erythrocytes, as potassium bicarbonates.
- Some CO2 combines with the amine radical of globin part of haemoglobin and
forms carbaminohaemoglobin.
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