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Regulation of respiration:

- The ability to maintain and moderate the respiratory rhythm according to the

demands of the body tissues is due to the neural control.

- A specialised centre present in the medulla region of the brain called respiratory

rhythm centre is primarily responsible for this regulation.

- Another centre present in the pons region of the brain called pneumotaxic centre

can moderate the functions of the respiratory rhythm centre.

- A chemosensitive area is situated adjacent to the rhythm center; it is highly

sensitive to CO2 and hydrogen ions.

- An increase in the concentration of these substances can activate this centre,

which in turn send signal to rhythm centre to make necessary adjustments in the

respiratory process.

- Receptors associated with aortic arch and carotid artery also can recognize

changes in CO2 and H+ concentration and send necessary signals to the

rhythm centre for remedial actions.

- Oxygen plays only an insignificant role in the regulation of respiratory rhythm.

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