Can there be mitosis without DNA replication in S phase?

The S - phase is the synthesis phase of a cell cycle in which DNA doubles or replicates before starting mitosis.

This phase also ensures doubling of the centrosome (a microtubule-organising structure).

Mitosis is the stage of cell cycle where the cell divides its chromosomal content in 2 equal sets and separates its cytoplasm, to give rise to 2 new daughter cells.

If the chromosomal duplication doesn’t occur, the genetic material will not be divided equally in both the newly forming cells. Hence, mitosis will not occur.

The correct answer is ‘No, mitosis cannot take place without DNA replication in S phase’